肿瘤内科 岳威

姓   名：岳威      性   别：男

出生年月：1990 年 08 月

专业技术职称： 副研究员

导师类别：硕导

电子邮箱：yuewei@bbmu.edu.cn

1. DNA 损伤修复缺陷在肿瘤发生发展中的作用

2. DNA 修复相关肿瘤标志物的筛选与功能验证

3. 基于 DNA 修复机制的肿瘤靶向治疗策略

1.国家自然科学基金青年项目 C 类，82504020 ，BRCA1 突变诱导中心体异常促进上皮性卵巢癌发生发展的机制研究，2026/01-2028/12， 30 万元，主持。

2.安徽省自然科学基金青年项目 C  类，2508085QH337 ，cAMP 介导卵巢癌铂类耐药的分子机制研究，202509-202708 ，8 万元，主持。

代表性论文：

1.Dedong  Yin#,  Pan  Wang#,  Yongcun  Hao#,  Wei  Yue#,  Xinran  Jiang#, Kuanming Yao, Yuqiong Wang, Xinxin Hang, Ao Xiao, Jingkun Zhou, Long Lin, Zhoulyu Rao, Han Wu, Feng Liu, Zaizai Dong, Meng Wu, Chenjie Xu, Jiandong Huang, Honglong Chang, Yubo Fan, Xinge Yu*, Cunjiang  Yu*,  Lingqian   Chang*,  Mo   Li* .  A  battery-free  nanofluidic intracellular    delivery    patch    for    internal    organs,    Nature,    2025, 642(8069):1051-1061.

2.Yuening Jiang, Jie Li, Tianzhen Wang, Xiaoyang Gu, Xinyu Li, Zhaofei Liu,  Wei  Yue*,  Mo  Li* .  VIPAS39  confers  ferroptosis  resistance  in epithelial ovarian cancer through exporting ACSL4, EBioMedicine, 2025, 114: 105646.

3.Taju Wu#, Fang Han#, Jinpei Mei, Jie Chen, Panpan Li, Mengyi Li, Jiaxin Shen, Xue Han, Rentian Song, Sainan Hou, Xinyu Li, Yutian Su*, Wei Yue*, Baohong Sun* . Photoactive metal-covalent organic framework nanozymes with enhanced peroxidase-mimicking activity for eliminating drug-resistant bacterial infections, J Colloid Interface Sci. 2025, 699(Pt 1):138178.

4.Wei Yue#, Xinyu Li#, Xiaolu Zhan#, Lei Wang, Jihong Ma, Meiyu Bi, Qilong Wang, Xiaoyang Gu, Bingteng Xie, Tong Liu, Hongyan Guo, Xin Zhu, Chen Song, Jie Qiao, Mo Li. PARP inhibitors suppress tumors via centrosome   error-induced   senescence   independent   of  DNA   damage response. EBioMedicine, 2024, 103:105129.

5.Wenjing Li, Guansheng Chen, Yongjun Wang, Yuening Jiang, Nanlin Wu, Mingjie Hu, Taju Wu*, Wei Yue* . Functional Analysis of BARD1 Missense Variants on Homology-Directed Repair in Ovarian and Breast Cancers, Molecular Carcinogenesis, 2024, 64(1): 91- 107.

6.Xinyu Li, Cuilian Zhang, Wei Yue*, and Yuening Jiang* . Modulatory effects  of cancer  stem  cell-derived  extracellular vesicles  on the tumor immune   microenvironment.    Frontiers    in    Immunology,   2024,    15: 1362120.

7.Yuening Jiang#, Wei Yue#, Meiyu Bi, Yuhan Guo, Xiaoyang Gu, Mo Li. Protocol for identifying metabolite biomarkers in uterine fluid for early ovarian cancer detection. STAR Protocols, 2024, 5(2): 102953.

8.Wei Yue, Jihong Ma, Yinan Xiao, Pan Wang, Xiaoyang Gu, Bingteng Xie, Mo Li. The apoptotic resistance of BRCA1-deficient ovarian cancer cells is mediated by cAMP. Frontiers in cell and developmental biology, 2022, 10:889656.

9.Bingteng Xie#, Xiaoling Liang#, Wei Yue#, Jihong Ma, Xinyu Li, Na Zhang, Pan Wang, Chang Liu, Xiaomeng Shi, Jie Qiao, Peng Zou, Mo Li. Targeting  cytokinesis  bridge  proteins  to  kill  high-CIN  type  tumors. Fundamental Research, 2021, 1(6):752-766.